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Modern Discontent


Publishing Independent Science Papers on COVID-19 and Occasional Opinion Pieces about Science and Culture. Be evidence driven not narrative driven.

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1.  May's Topic Post  

2022-05-15


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I apologize for sending this so late! We’re well into may so that unfortunately doesn’t provide much time in between seeing what people’s ideas …

3.  The LNP Mystery Part III  

2022-05-11


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A look at the "Highly Inflammatory" study, and things to consider with LNPs.

4.  The LNP Mystery Part II-1  

2022-05-10


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An addendum to yesterday's post and how I jumped the shark.

5.  The LNP Mystery Part II  

2022-05-09


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An examination of Dr. Palmer's brief assessment.

6.  The LNP Mystery Part I-1  

2022-05-05


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Evidence of the Haphazard SM-102 SDS change.

7.  The LNP Mystery Part I  

2022-05-04


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And a look into the SM-102 hubbub

10.  Delayed April Post  

2022-04-30


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Apologies for all of my paid members, but my April post may be late by a day or two. Unfortunately it’s one of those things that seemed to have …

14.  I did a Twitter naughty...  

2022-04-21


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I would say that I’m one of those boomers in a millenial’s body; I really don’t understand my generation. With that, I extensively avoid social …

15.  Cornering a Snake Venom Salesman  

2022-04-19


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Additional remarks on Dr. Ardis' doubling down and reactions to his snake venom theory.

16.  Frivolity Saturday and Easter Weekend  

2022-04-16


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My response to the “Watch the Water” documentary came relatively late, and at that time Dr. Ardis conducted several more interviews; all of whic…

17.  Beware of those Proposing "Snake Venom"  

2022-04-15


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An analysis of “Watch the Water” and the grave faults of the COVID dissenting community.

19.  The Erroneous Attempts at "Zero COVID"  

2022-04-12


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A few thoughts and ramblings about "zero COVID" and the current state of things

20.  Open Thread: The State of COVID Discourse  

2022-04-07


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As I work on a few different topics (as well as my taxes…) I wanted to get a feel from everyone as to their perspective on how the view the curr…

22.  Pharmacology: Applied Knowledge Answers  

2022-04-06


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If you find all of this information fruitful and important please subscribe. Also, if you would like to help fund my research endeavors and to keep most of this Substack free to the public, please consider becoming a paid member!Thank you for reading Modern Discontent. This post is public so feel fre...

23.  Substack is acting up  

2022-04-06


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Substack has been undergoing routine updates. Although they tend to improve features a lot of times it leads to a lot of issues. It appears this…

24.  The Illusion of Evidence-Based Medicine is Nothing New  

2022-04-04


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It’s only recently that more people have become aware

25.  March’s Voter Topic: The Battle over Germ and Terrain  

2022-03-31


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Does Germ Theory reign supreme, or does Terrain Theory hold merit?

26.  March's Topic: Germ vs Terrain Theory  

2022-03-31


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For those not in the know I am dabbling in having a monthly voter topic for my paid subscribers. This involves Subscribers providing a topic and…

28.  Does anyone bother reading studies?! (rant)  

2022-04-01


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Another Ivermectin study means more pontification rather than proper analysis.

29.  Frivolous Saturday QA  

2022-03-26


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As I look up research and finding more topics to write about I thought that today may be a good day to just start a conversation and see what is…

30.  An Introduction to Pharmacology  

2022-03-28


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A mini lesson on drug design and pharmaceuticals.

31.  Too Long; Didn't Send  

2022-03-29


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So I made a post yesterday about creating a new series of posts around general information. Many of my newsletters, especially the Anthology Ser…

33.  Feeling (Methylene) Blue Part I  

2022-03-22


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Dispelling the misinformation surrounding a new Tik Tok craze.

34.  Feeling (Methylene) Blue Part II  

2022-03-23


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Fact Checking the claims made by Tik Tok Influencers and the Media

35.  Long COVID Anthology Series  

2022-03-21


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A Collection of the Long COVID Posts & Citations

36.  Hair Loss, Impotence, and COVID  

2022-03-18


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Examining the more sensitive aspects of COVID.

37.  Open Discourse: Your Opinions on 2 Weeks until 2 Years to Flatten the Curve  

2022-03-16


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It’s a bit late in my area but it was only recently that I realized it’s been a little over two years since the start of the pandemic. So much h…

38.  The Complications of “Long COVID” Part IV  

2022-03-15


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Post-Vaccine Syndrome and Management & Treatment of Long COVID Symptoms

41.  The Complications of “Long Covid” Part I  

2022-03-10


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An introduction into “Long COVID”, where the name came from, and prior evidence of lingering viral symptoms.

42.  More on BioNTech's Lipid Nanoparticle Data  

2022-03-06


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Examining Radiolabeled Study 185350 and the Possible Implications

44.  Clarifying Yesterday's Lipid Nanoparticle Post  

2022-03-03


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Better information and more context to add.

45.  Preliminary Examination of BioNTech Data- Lipid Nanoparticles  

2022-03-02


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Taking a look at some of the data on LNPs, and why this does not bode well for the release of information.

46.  Before weighing in on Ukraine, make sure your comments are well-informed.  

2022-03-01


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Take a pause before deciding to engage in online debates, and know that you don't always have to provide your own two cents.

47.  The Remdesivir Anthology Series Archives  

2022-03-01


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A Collection of posts on Remdesivir and Citations

48.  The Hydroxychloroquine Anthology Series Archives  

2022-03-01


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A Collection of Posts about Hydroxychloroquine

49.  The Quercetin Anthology Series Archives  

2022-03-01


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A Collection of Works about Quercetin

50.  A Few New Coming Changes  

2022-02-27


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An Update to this Substack

52.  The Fluvoxamine Anthology Series  

2022-02-25


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A Collection of Fluvoxamine Posts including the "Pseudoinfection" Hypothesis

53.  Fluvoxamine Anthology Series Citations  

2022-02-25


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Because these Citations were too long

56.  Fluvoxamine- The Little SSRI that Could: Part IV  

2022-02-22


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Nonclinical Examination of Fluoxetine/Fluvoxamine & Emerging Clinical Trial Results

57.  Fluvoxamine- The Little SSRI That Could: Part III  

2022-02-16


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Nonclinical Examination of Fluvoxamine, Sigma-1 Agonism and ER Stress

58.  When things are "finally" over, what would you like to learn instead?  

2022-02-15


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As I am working on my Fluvoxamine series, it appears that all across the board many vaccine and mask mandates are ending. Hopefully this is a si…

59.  Notice: Check the Website for Longer Posts this Week  

2022-02-13


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I have been working on a series of posts about Fluvoxamine that have become more lengthy than I had expected, to the point that they are far too…

60.  Fluvoxamine- The Little SSRI That Could: Part II  

2022-02-13


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Nonclinical Examination of Lysosomotropism and the ASM/Ceramide Pathway

61.  Fluvoxamine: The Little SSRI that Could – Part I  

2022-02-09


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Brief Overview, Tortuous History, and Mechanisms of Action

62.  Everyone is Getting COVID. It’s time to learn and deal with the virus.  

2022-02-02


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PART III: Repurposed Drugs, A Culture of Shaming, and Citations

65.  Unfortunately, no Post this Week  

2022-01-28


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I've finally come down with "the sickness".

66.  The Curious Emergence of Omicron  

2022-01-19


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Part VI: Study Limitations, Concluding Remarks, & Citations

67.  The Omicron Anthology Series  

2022-01-20


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A Collection of the Preliminary Omicron Studies

68.  The Curious Emergence of Omicron  

2022-01-18


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Part V-1: Mice as the Possible Origins of Omicron

69.  The Curious Emergence of Omicron  

2022-01-16


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Part IV: Attenuated Lung Infection, Change in Disease Pathology?

70.  The Curious Emergence of Omicron  

2022-01-15


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Part III: Loss of Neutralizing Antibodies

71.  The Curious Emergence of Omicron  

2022-01-14


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Part I: Introduction and Examining Phylogenetic Trees

72.  The Curious Emergence of Omicron  

2022-01-14


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Part II: Omicron's Vastly Different Viral Behaviors

73.  OSHA's Mandate is Based on Outdated Science  

2022-01-07


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The attempts to dictate how people operate in the workplace are depending upon incoherent science and policies.

74.  The Monoclonal/Omicron Anthology Series  

2022-01-07


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A Collection of Posts on Monoclonal Antibodies & Omicron

75.  Have Monoclonal Antibodies Lost their Effectiveness? (Review)  

2022-01-05


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Part I: Overview of the Common Antibodies in Circulation

76.  Have Monoclonal Antibodies Lost their Effectiveness? (Review)  

2022-01-05


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Part II: Examining Molecular Modeling and Nonclinical Studies

78.  "Should Old Acquaintance be Forgot..." (Perspective)  

2021-12-31


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Struggling with the idea to “forgive” and “forget” in the coming New Year.

79.  Has the CDC Admitted to PCR Test Sensitivity?  

2021-12-29


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Today, CDC Director Dr. Walensky just stated PCR tests may stay positive for up to 12 weeks, well after people have commented on the test's high sensitivity.

80.  The Nasal Passage Anthology Series  

2021-12-29


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A series of newsletters looking into the nasal passage.

81.  Contextualizing the Death of John Eyers  

2021-12-27


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A Fitness Fanatic’s COVID Death, the media's agenda, and what it means to be “Healthy”.

82.  A Short Happy Holidays Message  

2021-12-24


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Let your troubles be miles away, if just for a weekend!

83.  The "Die Hard" Principle  

2021-12-23


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What makes a movie count as a Christmas movie?

84.  How NOT to Address the Nation  

2021-12-21


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If you want to encourage vaccinations, this is not the way to do it!

85.  The Hydroxychloroquine Anthology Series  

2021-12-22


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A Collection of my Hydroxychloroquine Posts

86.  “Just Don’t Look”  

2021-12-19


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If we ignore the media's constant bombardments, will we be able to return to normal?

87.  The Quercetin Anthology Series  

2021-12-19


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A Collection of my Quercetin Newsletters

88.  The Remdesivir Anthology Series  

2021-12-17


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A Collection of my Remdesivir Newsletters & Citations

93.  Remdesivir: COVID's Standard of Care that May be Causing more Harm than Good (REVIEW)  

2021-12-11


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Part III-2: Remdesivir in the Age of COVID (Examining the NIH Study)

95.  Final Remarks on the Molnupiravir Committee Meeting  

2021-12-06


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When mitigating a drug’s side effects is more important than halting approval.

96.  What I Learned Watching the Molnupiravir Committee Meeting (Review)  

2021-12-03


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The Bureaucratic Process, and the Alarming Molnupiravir Signals

98.  The Molnupiravir Anthology Series  

2021-12-01


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A Collection of my posts on Molnupiravir

99.  Oh, Omicron! Oh, Omicron! How Hysteric Should You Make Me?  

2021-11-30


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Renewed variant discussion brings more paranoia. Is it warranted, or should we be skeptical?

100.  The Results of Merck’s MOVe-OUT Study are in and...They’re not as Great as Expected  

2021-11-26


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The final results do not live up to the interim results. Why would there be a discrepancy?

101.  What has Attributed to Excess Drug Overdoses? Apparently not the Lockdowns.  

2021-11-24


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Media reporting seems to avoid mentioning the lockdown’s causative role in increasing rates of substance abuse.

102.  Quercetin: An Over-The-Counter Hydroxychloroquine, or Something More?  

2021-11-18


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Part III: Clinical Evidence, Perspective, and Concluding Remarks

106.  Long COVID: Valid Symptoms, or A Consequence of Mass Hysteria and Misinformation? (Paper Review & Perspective)  

2021-11-12


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A recent French study calls into question the prevalence of a persistent COVID talking point.

107.  Hydroxychloroquine: An Overview  

2021-11-10


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Part III-1: Cardiac Arrhythmia, Media Hysteria, and Institutional Capture

108.  Hydroxychloroquine: An Overview  

2021-11-10


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Part III-2: Cardiac Arrhythmia, Media Hysteria, and Institutional Capture (Continued)

109.  Hydroxychloroquine: An Overview  

2021-11-08


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Part I: History and General Medicinal Properties

110.  Hydroxychloroquine: An Overview  

2021-11-08


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Part II-1: Evidence as Treatment Against SARS-COV2

111.  Hydroxychloroquine: An Overview  

2021-11-08


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Part II-2: Evidence as Treatment Against SARS-COV2 (Continued)

112.  The UK Approves Usage of Molnupiravir Against COVID-19  

2021-11-04


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What does this mean for the rest of the world?

113.  The VAERS Data needs some Perspective  

2021-10-06


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We need to do more than look at the numbers.

114.  Taking this Substack Forward  

2021-10-10


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What Changes to Expect in the Future

115.  A Pathogen's Guide to the Nose (Review)  

2021-10-10


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Part I: Infection, Neuroinvasion, and Children

116.  A Pathogen's Guide to the Nose (Citations)  

2021-10-11


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Because apparently there's an email size limit.

117.  A Pathogen's Guide to the Nose (Review)  

2021-10-14


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Part II: Therapeutics, Prophylaxis, and Vaccination

119.  A Pathogen's Guide to the Nose (Review)  

2021-10-16


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Part III: At Home Nasal Remedies & Seasonal Concerns

121.  Rogan, Dr. Gupta and the Narrative of “Horse Dewormer” (Perspective)  

2021-10-19


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The Recent Rogan/Dr. Gupta Fallout Highlights the Faults of Today’s Media Apparatus

123.  About Original Antigenic Sin...  

2021-10-24


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Part I: Elaborating on the Hypothesis

124.  About Original Antigenic Sin...  

2021-10-24


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Part II: Correction to Previous UK Post, Applying it to SARS-COV2, and Concluding Remarks

125.  Boosting Our Way into Insanity (Rant)  

2021-10-26


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When at first it doesn’t succeed, try and try again-much to our dismay.

126.  Evidence of mRNA-Based Vaccine Traveling from Injection Site (Paper Review)  

2021-10-26


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A recent study contradicts a common establishment narrative about COVID vaccines.

128.  Evaluating the Evidence Around Molnupiravir (Perspective)  

2021-11-02


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Part II: Examining “Prior Evidence” & Concluding Remarks